Leadership: provide strong scientific, leadership at project level. Lead individual scientists and lab technicians on complex projects.
Projects: lead multi-disciplinary matrix teams on complex projects in the area of scientific expertise. Lead problem solving and lessons learned activities.
Scientific tasks: design advanced experimental plans and data analysis methods, write and review high quality reports.
Training: lead training activities in the area of expertise.
M.Sc. Biotechnology, Bioengineering, Chemical Engineering, Analytical Chemistry with 5-10 years experience
At least 3 years of experience in the mRNA field
Builds and leads a lab scientists and research associates focused on the development of encapsulated mRNA.
Codon optimization to improve RNA manufacturability, stability and translation.
Optimization of mRNA Untranslated regions (UTRs).
Template design ( pDNA, PCR, etc)
In-depth knowledge of mRNA analytics for determination of mRNA yield and purity parameters such has mRNA integrity, dsRNA, residual Protein and DNA.
Experience in sequencing (MiSeq, Sanguer, etc), UHPLC, Fragment analyzer, immunoassays, plate based assays, etc.